To bill it fully you need to regularly fire up Ipecac which will actually burst in your face. However, the tear delay boosts from both Brimstone and Ipecac are incorporated so the Brimstone beam takes a large size of your time to ask for. The massive damage increase from Ipecac currently functions in combination along with Brimstone’s extensive harm multiplier, resulting in a Brimstone ray of light which performs 565.5 damage in total (along with Isaac’s foundation statistics), sufficient to one-shot several of the Tummy bosses.
The Gallery almost always features a Bloodstream Bank and a Coin-operated Machine and/or Shell Game street person. The good news is, these “Timeless” enemies just appear in the activity’s tough mode, and they are completely missing from Rebirth.